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Venous stasis edema of bilateral lower limbs. Venous stasis edema of bilateral lower limbs Edem, vene varicoase

About the authors Abstract Thyroid pathology is rarely involved in the pathogenesis of sudden death in young people.

Inferior Vena Cava Hypoplasia Associated with Deep Vein Thrombosis – Case Presentation

We report here the cases of two young patients with decreased levels of thyroid hormones whose death was caused by an increased thrombotic status, with venous thrombosis and pulmonary thromboembolism. In both cases the thyroid pathology was not considered as the underlying cause of death as the association between this condition and venous thrombosis is still debatable.

However its presence may be considered a circumstantial factor, which could increase the severity of the disease and subsequently the lethality rate in pulmonary thromboembolism. An increased awareness for hypothyroidism or subclinical hypothyroidism in clinical practice may lead to a decrease in mortality secondary to thromboembolic disease.

Also, increased awareness for thyroid pathology during forensic autopsy in sudden deaths may lead to potentially significant results, that could explain some of the sudden death with an unknown cause, and decrease the number of the so called blank autopsies.

This has to do with the underlying cause of the varicose veins—the incompetency or defective valves in the vein, which promotes swelling.

There are three main thyroid causes of sudden death that are known and used in explaining the causes of death: thyrotoxicosis, myxedematous coma 11 Hecht L, Saeger W, Püschel KP. Plötzlicher Tod bei erkrankungen der schilddrüse und der nebenschilddrüsen.

Sudden unexpected death associated with lymphocytic thyroiditis. Med Sci Law. Coagulation disorders associated with thyroid disease are usually mild and not associated with sudden death. Subclinical hypothyroidism and deep venous thrombosis.

A pilot cross-sectional study. Thromb Haemost.

PPT - Venous system PowerPoint Presentation, free download - ID Cauze, complicaţii şi metode de tratament în insuficienţa venoasă cronică Venous stasis edema of bilateral lower limbs Edem, vene varicoase Tratamentul preventiv al varicelor în Kazan {{inebese. Edema leg swelling may affect both legs equally or may be more of a problem in one leg. The causes of swelling in one leg may be similar to the other leg, but it is not unusual for different factors to cause the swelling in each leg. Frequently, leg swelling is caused by more than [ ]. Tratamente anticelulitice cu varice Durere si edem asociate varicelor stabilizate; varice si hemoroizi in timpul sarcinii dupa cea de a patra luna.

Venous thromboembolism in patients hospitalized with thyroid dysfunction. Clin Appl Thromb Hemost. Risk of venous thromboembolism in patients hospitalized with hypothyroidism.

Edem, vene varicoase

Clinical review: Thyroid dysfunction and effects on coagulation and fibrinolysis: a systematic review. J Clin Endocrinol Metab. Pulmonary thromboembolism in infant: postmortem diagnosis. Rom J Leg Med. Death induced by pulmonary thromboembolism after caesarean section: A case report.

An anatomo-clinical analysis of autopsy cases].

Venous stasis edema of bilateral lower limbs

Patol Pol. Nihon Rinsho. The purpose of this article is to present two cases in which hypothyroidism was identified in patients with sudden death due to venous thrombosis complicated with pulmonary thromboembolism. The family denied the presence of este posibil sa facei o bar în varicoza other symptoms or preexistent diseases. Autopsy findings.

External examination found nothing except for a slightly increased circumference of the superior part of the right calf and bilateral 2nd degree calf varicosities. Internal examination revealed cerebral edema, a moderate degree of myocardial sclerosis, multinodular thyroid, bilateral pulmonary atelectasis, massive, bilateral pulmonary thromboembolism, hemorrhagic ovarian cysts, moderate adrenal hyperplasia, a Copper based intrauterine device IUDand a right saphenous thrombosis with an inflammatory reaction Figure 1.

Figure 1 Saphenous vein thrombosis. Histology findings. In both pulmonary arteries we identified thrombo-emboli with Zahn lines and hematic lysis.

Right saphenous vein contained a mixed thrombus with Zahn lines and hematic lysis. The wall of the right saphenous vein contained a polymorph inflammatory reaction.

Edem, vene varicoase Tratamentul preventiv al varicelor în Kazan {{inebese.

Thanatochemistry examination revealed a total T3 value of 3. Case 2 A year-old boy, basketball player, was brought by the Ambulance at the Emergency Department with cardiorespiratory arrest installed five minutes before their arrival. An ECG done at arrival showed electromechanical dissociation. The cause of the cardiac arrest has proven to be a massive thromboembolism, for which was started emergency thrombolysis.

In the first hour after thrombolysis the patient has numerous episodes of electromechanical dissociation and asystole, resuscitated each time. However, in less than 24 hours after admission the patient entered in multiple organ failure and was pronounced dead.

venous stasis edema of bilateral lower limbs

In his personal history is to be noted a prior orthopedic intervention about a month ago for femur slipped epiphyses, followed by cast immobilization with abduction bar at the knee level. The right pulmonary artery presented a massive, adherent thrombo-embolus.

Diagnosis and Management of Deep Venous Incompetence (Ulises Baltazar, MD)

Right lung had moderate atelectasis and stasis. We also found an enlarged thyroid, hepatic and kidney stasis, slipped epiphyses of the right femur, consolidated and bilateral thrombosis in the popliteal veins. Histology findings revealed a lung with acute respiratory distress syndrome incipient exudative phasesevere septum stasis, alveolar edema, areas of pulmonary atelectasis, and a relatively recent thromboembolism, partially occlusive in major right pulmonary branches associated with hemorrhage around the affected pulmonary vessels Figure 2.

The thyroid was normal.

venous stasis edema of bilateral lower limbs

Popliteal veins showed thrombophlebitis with incipient organization. Thanatochemistry examination revealed a total T3 of 0. Figure 2 Pulmonary thromboembolism, with partial lysis and hemorrhage around the vessel. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.

Endocr Pract. Subclinical hypothyroidism and the risk of coronary heart disease: a meta-analysis.

venous stasis edema of bilateral lower limbs

Am J Med. The Brazilian consensus for the clinical approach and treatment of subclinical hypothyroidism in adults: recommendations of the thyroid Department of the Brazilian Society of Endocrinology and Metabolism.

Arq Bras Endocrinol Metabol. Can subclinical hypothyroidism explain some sudden deaths due to pulmonary embolism without evident risk factors?

Med Hypotheses. Thyroid hormones can be used with caution for the diagnosis of either hypo or hyperthyroidism after death. T4 levels tend to decrease starting with 2. Postmortem values of thyroxine and thyroid stimulating hormone. J Forensic Sci. Postmortem behavior of serum thyroxine, triiodothyronine, and parathormone. Antemortem chemical hypothyroxinemia.

Venous system

Therefore high postmortem T4 levels can be used to diagnose hyperthyroidism. TSH levels however are known to be stable in serum at least 24 hours after death and are positively correlated with the values before death Coe J. In our cases, the first patient had a TSH value of In both cases, even if we identified increased values of TSH, we could not specifically state that the patients had hypothyroidism or subclinical hypothyroidism.

After death the vascular department of the body suffers profound changes, making the analysis of clotting disorders extremely difficult. Autolytic changes in blood cells of human cadavers.

Morphological studies. Forensic Sci Int. Platelets and serum proteins retain their normal function a few hours after blood cessation; afterwards stasis, hypoxia, decreased pH, and venous stasis edema of bilateral lower limbs alterations lead to the formation of postmortem blood cloths concomitant with fibrinolysis processes Böhm E, Hochkirchen K.

Zur ultrastruktur vitaler, postmortaler und autolysierter nicoflex varicoza. Strukturierende prinzipien hämostatischer prozesse.

Venous stasis edema of bilateral lower limb icd 10. Muguri de mesteacăn pe vodcă pentru varice

In deaths in which increased levels of catecholamine or plasminogen activator are released in the agonal period as is the case with most sudden deaths the thrombolytic events are increased and the cadaveric blood is liquid; if the agonal period is prolonged thrombotic events are dominant, leading to an increased density of postmortem clots Takeichi S, Tokunaga I, Hayakumo K, Maeiwa M.

Fluidity of cadaveric blood after sudden death: Part III. Acid-base balance and fibrinolysis. Am J Forensic Med Pathol. Fluidity of cadaveric blood after sudden death: Part I.

Postmortem fibrinolysis and plasma catecholamine level. Fluidity of cadaveric blood after sudden death: Part II. Mechanism of venous stasis edema of bilateral lower limbs of plasminogen activator from blood vessels.

For this reason we could not perform coagulation tests, that might have revealed the presence of additional risk factors for thromboembolism. In the second case, the patient had a significant risk factor for the development of thrombo-embolic disease orthopedic surgery followed by cast immobilization with bed-restable to explain by itself the unfavorable course. However the presence of an altered thyroid status may have increased the severity of the disease. However the presence of an altered thyroid status may be considered a circumstantial factor, which can increase the severity of the disease and subsequently the lethality rate in pulmonary thromboembolism.

venous stasis edema of bilateral lower limbs

Prospective studies with a larger number of patients should be conducted in order to identify more precisely the risk of deep venous thrombosis and pulmonary thromboembolism in patients with an altered thyroid status. An increased awareness for subclinical hypothyroidism in clinical practice may lead to a decrease in mortality secondary to thromboembolic disease.

Also, increased awareness for thyroid pathology during forensic autopsy in sudden deaths may lead to potentially significant results, able to explain some of the sudden death with an unknown cause and reduce the number of the so called blank autopsies. Publication Dates.

venous stasis edema of bilateral lower limbs